Death despite malaria prophylaxis

Tertian malaria (Plasmodium vivax and Plasmodium ovale) in two travelers despite atovaquone-proguanil prophylaxis.

There is limited data regarding the efficacy of prophylaxis with atovaquone/proguanil (A/P) against non-falciparum malaria in travelers. Two cases, one Plasmodium vivax infection and another Plasmodium ovale infection, in travelers despite A/P prophylaxis are presented.

Malaria prophylaxis for travellers.

Prophylaxis of Malaria

Malaria prevention in travelers to endemic areas remains dependent principally on chemoprophylaxis. Although malaria chemoprophylaxis refers to all malaria species, a distinction should be drawn between falciparum malaria prophylaxis and the prophylaxis of the relapsing malaria species (vivax & ovale). While the emergence of drug resistant strains, as well as the costs and adverse reactions to ...

Quinine Prophylaxis in Malaria

In the effect of quinine on the malarial parasite we have perhaps the most remarkable example of the specific action of a drug in the whole range of medicine and one which has stood the test of two and a half centuries. Yet we have the apparent paradox of the frequently reported failure of the drug prophylactically against malaria. It is abundantly proved that when a primary infection of malari...

Malaria Prophylaxis: A Comprehensive Review

The flow of international travellers to and from malaria-endemic areas, especially Africa, has increased in recent years. Apart from the very high morbidity and mortality burden imposed on malaria-endemic areas, imported malaria is the main cause of fever possibly causing severe disease and death in travellers coming from tropical and subtropical areas, particularly Sub-Saharan Africa. The impo...